Early-planted watermelons experienced higher disease incidence and greater yield losses from Fusarium wilt compared to later plantings, with yields reduced by over half in early plantings when inoculated with F. oxysporum f. sp. niveum. Later plantings saw yield reductions of 25% or less, resulting in yield savings of 5,000 to 15,000 lb/A, while the impact of Proline® 480 SC fungicide varied between sites, showing reduced disease but inconsistent yield benefits.